High Quality 99% Coluracetam Powder with Best Price CAS NO.135463-81-9
- FOB Price: USD: 3.00-3.50 /Gram Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
- Available Specifications:
99%(10-50)Gram99%(50-100)Gram
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Keywords
- Coluracetam
- 99% Coluracetam
- Coluracetam Powder
Quick Details
- ProName: High Quality 99% Coluracetam Powder wi...
- CasNo: 135463-81-9
- Molecular Formula: C19H23N3O3
- Appearance: White Powder
- Application: Pharmaceutical raw materials
- DeliveryTime: 3-7
- PackAge: 1-25kilogram?,two?aluminium?bags?insid...
- Port: Shanghai Tianjin port or Beijing Xi'an...
- ProductionCapacity: 1000 Kilogram/Week
- Purity: 99%
- Storage: Cool Dry Place
- Transportation: Shanghai Tianjin port or Beijing Xi'an...
- LimitNum: 1 Gram
- Moisture Content: 0.1%
- Impurity: 0.1%
Superiority
The company was established in August 2014. It is a modern advanced enterprise specializing in the research and production of API, natural plant extracts and active cosmetic ingredients.
The headquartered of the company is in the suburbs of Xi'an, covers an area of 50 acres, has a 10,000m2 ISO9001 standard factory; it has six professional production lines for extraction, evaporation, distillation, chromatography, etc., also a research, development center, an analysis, and testing center. The factory strictly controls and inspects the national prescription drug production indicators; currently, it has obtained FDA, HALAL, KASHER, and other related certificates.
Quality
The company is based on honest service, product quality is the highest requirement,andproduct variety is rich.
Price
We have the best price, if you need more quantity then we can also provide you with a more favorable price.
Details
Product Description
Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.
Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.
Item | Specifications | Results |
Assay(HPLC) | 98.0%~102.0% | 98.9% |
Appearance | Off-white crystalline powder | Complies |
Identification | IR | Complies |
Melting point | 156.0~160.0℃ | 157.0~158.0℃ |
Loss on drying | ≤0.5% | 0.11% |
Residue on ignition | ≤0.1% | 0.06% |
Related substance | ≤1.0% | 0.75% |
Heavy metals | ≤10ppm | Complies |
Function
Coluracetam is a nootropic agent of the racetam family. It may have potential use in prevention and treatment of ischemicretinopathy and retinal and optic nerve injury. Coluracetam has also been shown to reverse the loss of choline acetyltransferase production in the medial septal nucleus of rats exposed to phencyclidine (pcp), and is considered a potential therapeutic drug for schizophrenia.
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